Global Landscape Review of Serotype-Specific Invasive Pneumococcal Disease Surveillance among Countries Using PCV10/13: The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) Project
نویسندگان
چکیده
Serotype-specific surveillance for invasive pneumococcal disease (IPD) is essential assessing the impact of 10- and 13-valent conjugate vaccines (PCV10/13). The Pneumococcal Serotype Replacement Distribution Estimation (PSERENADE) project aimed to evaluate global evidence estimate PCV10/13 by age, product, schedule, syndrome. Here we systematically characterize summarize landscape routine serotype-specific IPD in PCV10/13-using countries describe subset that are included PSERENADE. Of 138 using as 2018, identified 109 with systems, 76 which met PSERENADE data collection eligibility criteria. received from most (n = 63, 82.9%), yielding 240,639 post-PCV10/13 introduction cases. Pediatric adult was represented all geographic regions but limited lower income high-burden countries. In PSERENADE, 18 sites evaluated PCV10, 42 PCV13, 17 both; used a 3 + 0 38 2 1, 13 9 mixed schedules. With such sizeable generally representative dataset, will be able conduct robust analyses PCV inform policy at national levels regarding immunization, product choice, including higher valency PCVs on horizon.
منابع مشابه
Global Coverage of Pneumococcal Conjugate Vaccine (PCV) and Serotype Distribution after Receiving Vaccine among Targeted PCV Vaccine Countries: A Systematic Review
Background and Objectives: After the introduction of the pneumococcal vaccine, an increase has been observed in the disease due to nonspecific stereotypes of the vaccine. This study was conducted to determine the spatial distribution of pneumococcal vaccine coverage and common stereotypes of streptococcus pneumonia after vaccine introduction in the vaccine recipient countries. Methods: The ...
متن کاملSystematic Evaluation of Serotypes Causing Invasive Pneumococcal Disease among Children Under Five: The Pneumococcal Global Serotype Project
BACKGROUND Approximately 800,000 children die each year due to pneumococcal disease and >90% of these deaths occur in developing countries where few children have access to life-saving serotype-based vaccines. Understanding the serotype epidemiology of invasive pneumococcal disease (IPD) among children is necessary for vaccine development and introduction policies. The aim of this study was to ...
متن کاملinvasive pneumococcal disease (ipd) serotype frequency in iranian patients
results the results of this study showed some s. pneumoniae serotypes were found in both sexes and some only in one sex invasive infections. for example, serotypes 10, 14, 18 and 22 were only in female patients with infections. conclusions the analysis of the results had suggested that serotypes 6 from lung and 19 from eye are the most abundant bacterial strains isolated from patients. the dise...
متن کاملSerotype replacement in disease after pneumococcal vaccination.
Vaccination with heptavalent pneumococcal conjugate vaccine (PCV7) has significantly reduced the burden of pneumococcal disease and has had an important public health benefit. Because this vaccine targets only seven of the more than 92 pneumococcal serotypes, concerns have been raised that non-vaccine serotypes (NVTs) could increase in prevalence and reduce the benefits of vaccination. Indeed, ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Microorganisms
سال: 2021
ISSN: ['2076-2607']
DOI: https://doi.org/10.3390/microorganisms9040742